LymphedemaV1, Main, Exploration, bibRecord, 002987

Inflammation-induced lymphangiogenesis and lymphatic dysfunction

Identifieur interne : 002987 ( Main/Exploration ); précédent : 002986; suivant : 002988

Inflammation-induced lymphangiogenesis and lymphatic dysfunction

Auteurs : Shan Liao [Canada] ; Pierre-Yves Von Der Weid [Canada]

Source :

Angiogenesis [ 0969-6970 ] ; 2014.

RBID : PMC:3981917

Abstract

The lymphatic system is intimately linked to tissue fluid homeostasis and immune cell trafficking. These functions are paramount in the establishment and development of an inflammatory response. In the past decade, an increasing number of reports has revealed that marked changes, such as lymphangiogenesis and lymphatic contractile dysfunction occur in both vascular and nodal parts of the lymphatic system during inflammation, as well as other disease processes. This review provides a critical update on the role of the lymphatic system in disease process such as chronic inflammation and cancer and examines the changes in lymphatic functions the diseases cause and the influence these changes have on the progression of the diseases.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981917

DOI: 10.1007/s10456-014-9416-7
PubMed: 24449090
PubMed Central: 3981917

Affiliations:

Le document en format XML

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<country xml:lang="fr" wicri:curation="lc">Canada</country>
<wicri:regionArea>Department of Microbiology, Immunology and Infectious diseases, Inflammation Research Network, Snyder Institute for Chronic Diseases, Faculty of Medicine, University of Calgary, Calgary, Alberta</wicri:regionArea>
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<front><div type="abstract" xml:lang="en"><p id="P1">The lymphatic system is intimately linked to tissue fluid homeostasis and immune cell trafficking. These functions are paramount in the establishment and development of an inflammatory response. In the past decade, an increasing number of reports has revealed that marked changes, such as lymphangiogenesis and lymphatic contractile dysfunction occur in both vascular and nodal parts of the lymphatic system during inflammation, as well as other disease processes. This review provides a critical update on the role of the lymphatic system in disease process such as chronic inflammation and cancer and examines the changes in lymphatic functions the diseases cause and the influence these changes have on the progression of the diseases.</p>
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Serveur d'exploration sur le lymphœdème

Inflammation-induced lymphangiogenesis and lymphatic dysfunction

Inflammation-induced lymphangiogenesis and lymphatic dysfunction

Source :

Abstract

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Le document en format XML

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